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Current Clinical Trials

At the University of Louisville's Section of Colon & Rectal Surgery, our patients are invited to work with us so that together we may refine and improve medical and surgicial treatments for inflammatory bowel disease and colorectal cancer.

To learn more about our ongoing studies, please contact our research coordinator Anna Williford, R.N., at (502) 583-0880 or email her.

Our patients may have the opportunity to participate in research by enrolling in the following clinical trial:

1.    A Phase 2/3 Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety and Efficacy of Golimumab Induction Therapy, Administered Intravenously, in Subjects with Moderately to Severely Active Ulcerative Colitis.
(Sponsor: Centocor)

2.    A Phase 3 Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety and Efficacy of Golimumab Maintenance Therapy, Administered Subcutaneously, in Subjects with Moderately to Severely active Ulcerative Colitis.
(Sponsor: Centocor)

3.    Prospective Real-World Observational Outcomes of Flexi-Seal® FMS (Proof) in the Management of ICU Patients with Transient Fecal Incontinence.
(Sponsor: ConvaTec)

4.    A 5-Year, Non-Interventional Registry Study of HUMIRA® (Adalimumab) in Patients with Moderately to Severely Active Crohn’s Disease (CD).
(Sponsor: Abbott Laboratories)

5.    Prospective open-label study of a smokeless tobacco product in Crohn's disease patients with moderately to severely active Crohn's disease who have failed prior attempts at smoking cessation.
(Sponsor: Foundation for Clinical Research in IBD)

6.    Anorectal Motility in Patients with Crohn's Disease.
(Sponsor: Dr. Galandiuk)

7.    The Association of Gastrointestinal Disease, DNA Repair and Host Defense Genes.
(Sponsor: Dr. Galandiuk)

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