Current Clinical Trials

At the University of Louisville's Section of Colon & Rectal Surgery, our patients are invited to work with us so that together we may refine and improve medical and surgicial treatments for inflammatory bowel disease and colorectal cancer.

To learn more about our ongoing studies, please contact our research coordinator Anna Williford, RN, at (502) 583-0880 or email her.

Our patients may have the opportunity to participate in research by enrolling in the following clinical trial:

1.    A randomized controlled trial to compare the functional outcome and quality of life of patients with low rectal cancer who undergo a J-Pouch or a side to end coloanal anastomosis.
(Sponsor: The Cleveland Clinic)

2.    Protocol C13007/ A Phase 3, Randomized, Placebo-Controlled, Blinded, Multicenter Study of the Induction and Maintenance of Clinical Response and Remission by Vedolizumab (MLN0002) in Patients with Moderate to Severe Crohn’s Disease.
(Sponsor: Millennium Pharmaceutical, Inc.)

3.    Protocol C13008/ A Phase 3, Open-label Study to Determine the Long-Term Safety and Efficacy of MLN0002 in Patients with Ulcerative Colitis and Crohn’s Disease.
(Sponsor: Millennium Pharmaceutical, Inc.)

4.    A 5-Year, Non-Interventional Registry Study of HUMIRA^® (Adalimumab) in Patients with Moderately to Severely Active Crohn’s Disease (CD).
(Sponsor: Abbott Pharmaceutical, Inc.)

5.    Prospective open-label study of a smokeless tobacco product in Crohn's disease patients with moderately to severely active Crohn's disease who have failed prior attempts at smoking cessation.
(Sponsor: Galandiuk, S.)

6.    The Association of Gastrointestinal Disease, DNA Repair and Host Defense Genes.
(Sponsor: Galandiuk, S.)